Department of Clinical Research

A clinical trial is a study whereby the subjects are the patients. In the United States approximately 10% of medicines that enter the clinical evaluation process are eventually given permission to be sold. Designing and implementing a good clinical trial requires the cooperation of a physician or a clinical pharmacologist with a statistician and many other specialists. The main goal of a clinical trial is to evaluate a new treatment for a disease and/or to find a suitable prevention mechanism for an illness or a complication including but not limited to death and physical disability
 


In general, the most important goals of clinical studies include

Developing a logical connection between the laboratory and clinical research
Determining the effectiveness of interventions in progress
Facilitating interventions that seem to have been successful

 

The purpose of researchers in clinical trials is testing therapeutic methods on studied subjects and observing their effects. By using various methods such as randomized distribution or blind studies, researchers try to eliminate or minimize possible effects of bias in study results
 


A comprehensive definition of clinical study is the following

Any study done on humans to discover or verify the clinical and medical effects or pharmacodynamic effects of a research product, to identify any adverse reactions to a research product, or to study the absorption, distribution, metabolism, and excretion of a research product in order to prove its safety or efficacy

A good and ethical clinical practice includes the following

International standards of design
Proper implementation
Monitoring and inspection
Data entry
Analysis
Reporting of clinical trials
 


Various stages of designing a clinical trial include

Selection of patients
Determining the number of required patients
Random distribution of patients into research groups
Blinding the study to avoid any bias
Determining the inclusion and exclusion criteria
Measuring the basic variables
Evaluating the responses of each patient
Observing any occurred side effects during the study
Preparing the final report
 


The main types of studies used in clinical trials include

Longitudinal studies: this is a type of an observational study in which a process is studied over a long period of time, such as a cohort study or a case-control study
Cross-sectional studies: this is a type of an observational study in which collected data is examined at a particular point in time and the data is more descriptive
 

Due to the fact that herbal medicines have been well embraced, conducting clinical trials in order to ensure their effectiveness and safety use has been a priority on this department’s agenda. The goal of the department of clinical research is to provide effective and safe medicines with minimal side effects. In this regard, numerous research studies have been conducted and their articles have been published in national and international journals


Research Goals

Management of clinical trials for the production of herbal medicines
Training the therapeutic courses related to medicinal herbs
Developing therapeutic herbs
 


Members

Maryam Nikzad, MD—Clinical Expert
MahnazMahlooji, Bachelor of Midwifery—Clinical Expert

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